AZD3759 hydrochloride ( —— )

产品货号. M18097 CAS No. 1626387-81-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

AZD3759 hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrantEGFRinhibitor.
产品描述

AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrantEGFRinhibitor. At KmATP concentrations, theIC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
同义词

——
通路

Others
靶点

Other Targets
受体

EGFR (exon 19De); EGFR (L858R); EGFR (wt)
研究领域

——
适应症

——

CAS Number

1626387-81-2
分子量

496.36
分子式

C22H24Cl2FN5O3
纯度

98%
溶解度

——
SMILES

C[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C.Cl
化学全称

——

1. Zeng Q, et al. J Med Chem. 2015 Oct 22;58(20):8200-15.

计算器

产品手册

关联产品

Hydroxy-gamma-sansho...

Hydroxy-γ-sanshool is a pungent compound, it can cause oral numbness.
Aloin

Aloin, a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
3-O-Methylducheside ...

3-O-Methylducheside A is a natural product for research related to life sciences.